Original Article BIOACTIVE COMPOUNDS FROM SPONGE SUBERITES CARNOSUS (JOHNSTON) COLLECTED FROM WEST COAST OF MUMBAI, INDIA

نویسندگان

چکیده

Objective: Structural elucidation of bioactive compounds from marine Sponge Suberites Carnosus (Johnston) by using Thin Layer Chromatography (TLC), Gas Chromatography-Mass Spectrometry (GC-MS), Fourier Transform Infrared Spectrometer (FTIR) techniques with respect to its pharmacological and biomedical properties.
 Methods: The sponge carnosus was collected during low tides West Coast Mumbai. Crude extract obtained taking 10 gram sample in10 ml methanol. preparative TLC (Thin Chromatography) performed Toluene: Ethyl acetate: Diethylamine (7:2:1) (v/v). isolated were subjected GC-MS FTIR analysis.
 Results: From the analysis, total ten identified. spectra correlate mass spectra. structures those are 6-Fluoro 2-trifluromethylbenzoic acid,2,3-dichlorophenyl ester, Eicosane 3-cyclohexyl, Phosphine imide, P,P,P,-tris (p-chlorophenyl)-N-phenyl-, Dimethylhyl hexavinyl octasilsesquioxane, Hexanoicacid, hexadecyl Hexadecanoic acid,2-hydroxy1-(hydroxymethyl)ethyl 9, 19-Cyclolanostan-3-ol, acetate, (3β), Tetracosane, 3-ethyl-, 11, 14-Eicosadienoic acid, methyl Triacontane, 11,20-didecyl-respectively.
 Conclusion: nature biological properties said determined it found that some them act as a skin irritant. Some have fatty, metabolite, irritant property, whereas masking perfuming agents. highly toxic others an effect on health environmental hazard. corrosive in nature, Cholesterol chemotaxonomic significance.

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ژورنال

عنوان ژورنال: International Journal of Pharmacy and Pharmaceutical Sciences

سال: 2021

ISSN: ['0975-1491', '2656-0097']

DOI: https://doi.org/10.22159/ijpps.2021v13i6.40794